SP-0590: Novel developments in paediatric cancer

Novel developments in angiogenesis cancer therapy

A greater understanding of the factors and pathways controlling angiogenesis in tumours has allowed the development of a number of agents that selectively inhibit the pathways mediating that activity. The results to date of clinical trials with such agents and future research opportunities are reviewed.

Recent Developments in Understanding Paediatric Barrett's Oesophagus

Barrett’s oesophagus (BO) is an acquired pre-malignant condition in which metaplastic columnar epithelium replaces the normal squamous mucosa as a consequence of chronic gastro-oesophageal reflux. The pre-malignant quality of BO is demonstrated in untreated adults with BO which are at risk of Barrett-associated adenoacarcinoma (BAA). This review addresses the epidemiological, clinical, endoscop...

Vaccinations in Paediatric Rheumatology: an Update on Current Developments

In 2011, the European League Against Rheumatism (EULAR) published recommendations regarding the vaccination of children with rheumatic diseases. These recommendations were based on a systematic literature review published in that same year. Since then, the evidence body on this topic has grown substantially. This review provides an update of the systematic literature study of 2011, summarizing ...

Recent developments in the understanding of paediatric musculoskeletal pain syndromes.

Recent developments in airway management of the paediatric patient.

PURPOSE OF THE REVIEW During the last two years, several studies have enhanced our knowledge about the influence of pharmacological agents and routine airway management manoeuvres on the airway of paediatric patients. New supraglottic airway devices have been introduced into routine paediatric anaesthesia practice, and the design of paediatric endotracheal tubes has been modified. This review s...